The purpose of this study is to find out if an investigational meningitis vaccine is safe and can help prevent meningococcal disease when given to healthy children ages 11 to 17 years old.  Duration:  Up to 14 months Number of … Read more

The purpose of this study is to evaluate the safety, efficacy, and tolerability of Chantix versus a placebo in adolescent smokers who are motivated to quit smoking. Duration:  Up to 1 year Number of visits to CKRA:  At least 23 … Read more

The purpose of this study is to help determine whether patients taking inhaled corticosteroids together with salmeterol have the same risk of having uncommon but serious problems due to asthma when compared to patients taking inhaled corticosteroids alone. Duration:  Approximately … Read more

The purpose of this study is to assess the effectiveness of pregabalin (Lyrica) compared to a placebo in subjects who have diabetic peripheral neuropathy (DPN) who use NSAIDs for the treatment of conditions other than DPN. Duration:  Approximately 18 weeks … Read more

The purpose of this study is to identify and treat subjects who have both fibromyalgia and depression who are taking an antidepressant for their depression, and to determine whether pregabalin improves pain associated with fibromyalgia compared to a placebo in … Read more

The purpose of this study is to further evaluate the efficacy of Krystexxa in adult patients with gout. Duration:  Approximately 63 weeks Number of visits to CKRA:  Approximately 25 Compensation:  $30 per completed visit NOTE:  Qualified participants must be at … Read more

The purpose of this study is to evaluate the safety and effectiveness of an investigational medication in male subjects with low testosterone, otherwise known as “hypogonadism”. Duration:  Up to 58 weeks Number of visits to CKRA:  Up to 17 Compensation:  … Read more

This study is designed to help determine how safe an investigational vaccine is and how it works in subjects who have melanoma.   Duration:  Approximately 2 years. Number of visits to CKRA:  15 Compensation:  $50 per visit Note:  Qualified participants … Read more

The purpose of this study is to compare the effectiveness and tolerability of three concentrations of an investigational nasal spray versus a placebo nasal spray for the treatment of nocturia. Duration:  Approximately 16 weeks Number of visits to CKRA:  Up … Read more

The purpose of this study is to compare the effectiveness of two doses of a drug called fesoterodine to a placebo for overactive bladder. Duration:  Up to 16 weeks Number of visits to CKRA:  3 to 4 Compensation:  Up to … Read more

The purpose of this study is to find out if the prescription drug Xerese, which has already been approved by the FDA to treat cold sores in adults and adolescents 12 years old and older, is safe to use on … Read more

The purpose of this study is to examine important safety aspects of the drugs varenicline (Chantix) and buproprion (Wellbutrin, Zyban) compared to nictoine-replacement therapy (nicotine patch) and placebo in smokers and to examine how well varenicline, buproprion and nicotine-replacement therapy will … Read more

The purpose of this study is to assess the safety and tolerability of an investigational medication when combined with insulin to see if it can help reduce mean daily glucose, improve glycemic control, and reduce overall insulin requirements.   Duration:  … Read more

The purpose of this study is to evaluate cardiovascular outcomes after treatment with Exenatide once weekly in patients with Type 2 Diabetes. Duration: Approximately 4 years Number of visits to CKRA: Approximately 12 Compensation: Up to $30 per completed visit … Read more

The purpose of this study is to evaluate the safety and efficacy of a new medication and stigaliptin (Januvia) added to metformin in adult patients who are not adequately controlled on metformin alone or in combination with other diabetes medications. … Read more